Noninvasive method for estimating glucose blood constituents
AssigneeAnalytics For Life Inc.
InventorsSunny Gupta, Timothy Burton, Matthew Howe-Patterson
Life of this patent
Estimating the term…
Abstract
A light-based method and technique for measuring the static and average plasma glucose concentration over a prolonged period of time. More specifically, the disclosure relates to a method that utilizes mathematical analysis of appendage mobile LED flash IR light transmittance, absorption and scattering by using high resolution mobile camera data to estimate the concentration of glucose and glycated hemoglobin (HbA1c) in millimoles per liter (mmol/L).
Claims25
A method of performing blood constituent analysis, comprising:
- receiving a series of captured images that contain a digital signature of absorbed, transmitted and scattered light from a soft tissue appendage;
- determining a power spectral density (PSD) time series data from the digital signature;
- performing a model-based analysis to transform the PSD time series data to a noiseless model,
- applying a genetic algorithm to the noiseless model to estimate a level of blood constituent as a function of features that are extracted from a database of perfusion videos having associated blood panels;
- and
- communicating the level of blood constituent in a format suitable for display.
A system for performing light-based tissue perfusion blood constituent analysis, comprising:
- a capture device that captures a series of images that contain a digital signature of absorbed, transmitted and scattered light from a soft tissue appendage;
- a processor that:
- receives the series of images and determines power spectral density (PSD) time series data from the digital signature;
- performs a model-based analysis to transform the PSD time series data to a noiseless model;
- applies a genetic algorithm to the noiseless model to estimate a level of blood constituent as a function of features that are extracted from a database of perfusion videos having associated blood panels;
- and
- a display that displays the level of blood constituent.
A method for estimating blood constituent analysis, comprising:
- capturing a series of images using a mobile device having a camera that includes a digital signature of absorbed, transmitted and scattered light from a soft tissue appendage;
- obtaining a power spectral density (PSD) time series data from the series of images;
- performing a model-based analysis to transform the PSD time series data to a noiseless model;
- applying a genetic algorithm to the noiseless model to estimate a level of blood constituent as a function of features that are extracted from a database of perfusion videos having associated blood panels;
- and
- presenting the level of blood constituent in a display of the mobile device.
A device, comprising:
- a memory that stores computer readable instructions;
- a camera that includes a complementary metal-oxide semiconductor (CMOS) sensor;
- and one or more processors coupled to the memory, the one or more processors executing the computer-readable instructions to:
- capture, using the camera, a series of images having a digital signature of absorbed, transmitted and scattered light from a soft tissue appendage;
- obtain power spectral density (PSD) time series data from the series of images;
- perform a model-based analysis to transform the PSD time series data to a noiseless model;
- apply a genetic algorithm to the noiseless model to estimate a level of blood constituent as a function of features that are extracted from a database of perfusion videos having associated blood panels;
- and
- present the level of blood constituent in a display of the device.
Dependencies are inferred from the claim text.