Cross-reactive T-cell epitopes of HIV, SIV, and FIV for vaccines in humans and cats
AssigneeUniversity of Florida Research Foundation, Inc.
InventorJanet K. Yamamoto
Life of this patent
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Abstract
The subject invention concerns methods and materials for inducing an immune response in an animal or person against an immunodeficiency virus, such as HIV, SIV, or FIV. In one embodiment, a method of the invention comprises administering one or more antigens and/or immunogens to the person or animal wherein the antigen and/or immunogen comprises one or more evolutionarily conserved epitopes of immunodeficiency viruses. In one embodiment, the epitope is one that is conserved between HIV and FIV.
Claims20
A method for inducing an immune response in a person or animal against an immunodeficiency virus, comprising administering one or more antigens and/or immunogens to the person or animal, wherein said one or more antigens and/or immunogens comprise one or more evolutionarily conserved epitopes, wherein said epitopes are conserved between two or more different immunodeficiency viruses, and wherein said epitopes independently consist of the amino acid sequence of any of SEQ ID NOs:
- 1 to 37 or SEQ ID NOs:39 to 102.
Dependencies are inferred from the claim text.