Back to results
US 10,556,967 B2Granted
Anti-ADAM28 antibody for treating cancer
AssigneesGeneFrontier Corporation, Keio University
InventorsAkira Miyakoshi, Rena Matsumoto, Shizue Katoh, Yuki Hayami, Satsuki Mochizuki, Masayuki Shimoda, Yasunori Okada
Life of this patent
Estimating the term…
Abstract
The present invention provides an antibody that specifically binds to human ADAM28, inhibits enzyme activity of human ADAM28, and has an activity to suppress metastasis of a cancer cell that expresses human ADAM28. The antibody of the present invention can be a human antibody.
Claims14
An antibody specifically binding to human ADAM28 and having an activity to inhibit enzyme activity of human ADAM28, which antibody comprises a light chain variable region and a heavy chain variable region,
- wherein
- the light chain variable region comprises CDR1 comprising the amino acid sequence shown in SEQ ID NO:
- 5, CDR2 comprising the amino acid sequence shown in SEQ ID NO:
- 6, and CDR3 comprising the amino acid sequence shown in SEQ ID NO:
- 7, and
- the heavy chain variable region comprises CDR1 comprising the amino acid sequence shown in SEQ ID NO:
- 8, CDR2 comprising the amino acid sequence shown in SEQ ID NO:
- 9, and CDR3 comprising the amino acid sequence shown in SEQ ID NO:
- 10.
6 more elements
Dependencies are inferred from the claim text.