System, method and computer-accessible medium for obtaining and/or determining mesoscopic structure and orientation with fiber tracking
AssigneesNew York University, Albert-Ludwigs-Universität Freiburg
InventorsDmitry S. Novikov, Valerij Kiselev, Marco Reisert
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Abstract
Exemplary systems, methods, and computer-accessible mediums can be provided that can generate resultant data regarding fiber tract(s) and anatomical structure(s). For example, first information related to imaging data of the anatomical structure(s) can be received. Second information related to a predictive model of further fiber tract(s) can be received. The resultant data can be generated based on the first information, the second information and a fiber cost procedure.
Claims24
A non-transitory computer-accessible medium having stored thereon computer-executable instructions for generating resultant data regarding a plurality of fiber tracts of at least one anatomical structure, wherein, when a computer hardware arrangement executes the instructions, the computer arrangement is configured to perform procedures comprising:
- receiving first information related to imaging data of the at least one anatomical structure;
- receiving second information related to a predictive model of at least one further fiber tract that is based on (i) biophysical mesoscopic model parameters of neuronal tracts, and (ii) geometric model parameters of the neuronal tracts, wherein the biophysical mesoscopic model parameters include a diffusion coefficient, and wherein the neuronal tracts comprise a plurality of segments each having a different set of diffusion parameters that are based on the first information;
- and
- generating the resultant data by simultaneously optimizing the biophysical mesoscopic model parameters and the geometric model parameters based on a fiber cost procedure that is based on (i) a polymerization of the segments into the fiber tracts, and (ii) a distance between a measured magnetic resonance imaging (MRI) signal for the segments and a predicted MRI signal for the segments.
A system for generating resultant data regarding a plurality of fiber tracts of at least one anatomical structure, comprising:
- a computer hardware arrangement configured to:
- receive first information related to imaging data of the at least one anatomical structure;
- receive second information related to a predictive model of at least one further fiber tract that is based on (i) biophysical mesoscopic model parameters of neuronal tracts, and (ii) geometric model parameters of the neuronal tracts, wherein the biophysical mesoscopic model parameters include a diffusion coefficient, and wherein the neuronal tracts comprise a plurality of segments each having a different set of diffusion parameters that are based on the first information;
- and
- generate the resultant data by simultaneously optimizing the biophysical mesoscopic model parameters and the geometric model parameters based on a fiber cost procedure, wherein the fiber cost procedure is based on (i) a polymerization of the segments into the fiber tracts and (ii) a distance between a measured magnetic resonance imaging (MRI) signal for the segments and a predicted MRI signal for the segments.
A method for generating resultant data regarding a plurality of fiber tracts of at least one anatomical structure, comprising:
- receiving first information related to imaging data of the at least one anatomical structure;
- receiving second information related to a predictive model of at least one further fiber tract that is based on (i) biophysical mesoscopic model parameters of neuronal tracts, and (ii) geometric model parameters of the neuronal tracts, wherein the biophysical mesoscopic model parameters include a diffusion coefficient, and wherein the neuronal tracts comprise a plurality of segments each having a different set of diffusion parameters that are based on the first information;
- and
- generating the resultant data by simultaneously optimizing the biophysical mesoscopic model parameters and the geometric model parameters based on a fiber cost procedure, wherein the fiber cost procedure is based on (i) a polymerization of the segments into the fiber tracts and (ii) a distance between a measured magnetic resonance imaging (MRI) signal for the segments and a predicted MRI signal for the segments.
Dependencies are inferred from the claim text.