System and apparatus for porously-encapsulated magnetic-nanoparticle biosensors

A system for measuring an analyte concentration in a solution comprising:

• a plurality of nanocontainers having porous walls, the nanocontainers containing a plurality of magnetic nanoparticles, the magnetic nanoparticles coated with a selective binder capable of selectively binding a substance selected from the group consisting of the analyte, an indicator substance releasable from the selective binder by the analyte, and an indicator substance cleavable by the analyte;
• apparatus for exposing the nanocontainers to the solution;
• and
• magnetic spectroscopy of Brownian motion sensing apparatus for detecting agglutination or aggregation of the nanoparticles;
• wherein the selective binder capable of selectively binding the analyte is selected from the group consisting of a nucleic acid strand, a protein, and a combination of nucleic acid strands and protein;
• wherein the nanocontainers are nanocontainers are less than one millimeter in largest dimension;
• and
• where the apparatus for exposing the nanoparticles to the solution comprises a well of a multiple-test plate within which the nanocontainers containing the nanoparticles are deposited.