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US 10,501,792 B2Granted
Nanochannel compositions and methods
OwnerSeth Harvey Lichter, Thomas Brian Sisaninventors
Life of this patent
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Abstract
Disclosed herein is a composition comprising a nanochannel and a contained substance, wherein the nanochannel comprises a single-file nanochannel and the contained substance comprises a plurality of substance particles arranged in a single-file chain within the nanochannel. Methods and systems for molecular transport of a substance through a nanochannel are also provided that rely upon the use of nanojumps, where nanojumps mediate the transport through the nanochannel.
Claims94
A composition comprising a nanotube having a length and a substance contained within the nanotube, said substance comprising a plurality of substance particles arranged in a single-file fashion along the length of the nanotube,
- wherein said substance particles are arranged to include at least one nanojump,
- wherein said nanojump comprises a localized region within said nanotube wherein the average density of the substance particles within said nanojump differs from the average density of the substance particles in regions of similar size outside of said nanojump but within the same nanotube, and
- wherein the substance particles in said regions of similar size outside of said nanojump but within the same nanotube are relatively stationary as substance particles within said nanojump region are transported along said nanotube by said nanojump.
An array of nanotubes,
- each nanotube having a length and each nanotube containing a substance within the nanotube,
- said substance comprising a plurality of substance particles arranged in a single-file fashion along the length of the nanotube, and wherein said substance particles are arranged to include at least one nanojump,
- wherein said nanojump comprises a localized region within said nanotube wherein the average density of the substance particles within said nanojump differs from the average density of the substance particles in regions of similar size outside of said nanojump but within the same nanotube,
- wherein the substance particles in said regions of similar size outside of said nanojump but within the same nanotube are relatively stationary as substance particles within said nanojump region are transported along said nanotube by said nanojump.
1 more element
A method of moving a substance from within a nanotube to an exterior position comprising:
- (a) arranging a plurality of particles of said substance in a single-file fashion along the length of said nanotube,
- (b) forming at least one nanojump within said nanotube,
- wherein said nanojump comprises a localized region within said nanotube wherein the average density of the substance particles within said nanojump differs from the average density of the substance particles in regions of similar size outside of said nanojump but within the same nanotube, and
- wherein the substance particles in said regions of similar size outside of said nanojump but within the same nanotube are relatively stationary as substance particles within said nanojump region are transported along said nanotube by said nanojump.
1 more element
A method of sequencing a strand of a substance comprising multiple subunits comprising:
- moving at least part of a strand of a substance lengthwise through a nanotube by forming at least one nanojump within said nanotube,
- wherein said nanojump comprises a localized region within said nanotube wherein the average density of the substance within said nanojump differs from the average density of the substance in regions of similar size outside of said nanojump but within the same nanotube;
- and
- advancing said substance from within the nanotube by the passage of said at least one nanojump to a location outside of the nanotube by an amount equal to about one single subunit of said substance;
- wherein the substance subunits in said regions of similar size outside of said nanojump hut within the same nanotube are relatively stationary as substance subunits within said nanojump region are transported along said nanotube by said nanojump;
- and
- measuring one or more properties of said one single subunit.
4 more elements
A method of transporting at least one charged particle through a nanotube comprising:
- arranging a chain of substance particles contained within said nanotube in a single file fashion along the length of the nanotube;
- and
- forming at least one nanojump within said nanotube,
- wherein said nanojump comprises a localized region within said nanotube wherein the average density of the substance particles within said nanojump differs from the average density of the substance particles in regions of similar size outside of said nanojump but within the same nanotube, and
- wherein the substance particles in said regions of similar size outside of said nanojump but within the same nanotube are relatively stationary as substance particles within said nanojump region are transported along said nanotube by said nanojump, and
- transporting a charged particle along the chain of substance particles.
3 more elements
A system for transporting a substance through a nanotube comprising:
- (a) a nanotube having a length and a substance contained within the nanotube, said substance comprising a plurality of molecules arranged in a single-file fashion-along the length of the nanotube, and
- (b) a nanojump-forming device coupled to said nanotube,
- wherein
- (1) said nanojump comprises a localized region within said nanotube wherein the average density of the substance particles within said nanojump differs from the average density of the substance particles in regions of similar size outside of said nanojump but within the same nanotube, and
- (2) wherein the substance particles in said regions of similar size outside of said nanojump but within the same nanotube are relatively stationary as substance particles within said nanojump region are transported along said nanotube by said at least one nanojump.
2 more elements
A method of generating power comprising:
- transporting a substance comprising a plurality of substance particles through a nanotube,
- wherein at least a portion of said substance particles couple with at least a or some electrons in the wall of said nanotube yielding an electrical current,
- wherein said nanotube has a diameter that is:
- (a) larger than the diameter of a single particle of said substance and two atomic radii of the appropriate constituent of the nanotube wall, and
- (b) smaller than twice the diameter of a single particle of said substance and two atomic radii of the appropriate constituent of the nanotube wall,
- wherein said method further comprises forming at least one nanojump,
- wherein said nanojump comprises a localized region within said nanotube wherein the average density of the substance particles within said nanojump differs from the average density of the substance particles in regions of similar size outside of said nanojump but within the same nanotube, and
- wherein the substance particles in said regions of similar size outside of said nanojump but within the same nanotube are relatively stationary as substance particles within said nanojump region are transported along said nanotube by said at least one nanojump.
5 more elements
A method of creating one or more than one nanojump in a nanotube with a substance contained therein, said substance comprising a plurality of particles arranged in a single file fashion along the length of the nanotube, by applying a periodic field to said substance,
- wherein said nanojump comprises a localized region within said nanotube wherein the average density of the substance particles within said nanojump differs from the average density of the substance particles in regions of similar size outside of said nanojump but within the same nanotube, and
- wherein the substance particles in said regions of similar size outside of said nanojump but within the same nanotube are relatively stationary as substance particles within said nanojump region are transported along said nanotube by said at least one nanojump.
A method of transporting a substance in a nanotube comprising:
- forming at least one nanojump in a nanotube comprising a substance, said substance comprising a plurality of substance particles arranged in a single file fashion along the length of the nanotube;
- and transporting said substance by the passage of at least one nanojump,
- wherein said nanojump comprises a localized region within said nanotube wherein the average, density of the substance particles within said nanojump differs from the average density of the substance particles in regions of similar size outside of said nanojump but within the same nanotube, and
- wherein the substance particles within said regions of similar size outside of said nanojump but within the same nanotube remain relatives stationary as substance particles within said nanojump region are transported along said nanotube by said at least one nanojump.
1 more element
A method of controlling a chemical reaction comprising:
- filling a first nanotube with a substance comprising a plurality of substance particles arranged in a single file fashion along the length of said first nanotube,
- forming at least one nanojump within said first nanotube,
- wherein said nanojump comprises a localized region within said first nanotube wherein the average density of the substance particles within said nanojump differs from the average density of the substance particles in regions of similar size outside of said nanojump but within said first nanotube;
- and
- wherein the substance particles within said regions of similar size outside of said nanojump but within the first nanotube remain relatively stationary as substance particles within said nanojump region are transported along said first nanotube by said at least one nanojump;
- forming a second nanotube containing a substance comprising a plurality of substance particles arranged in a single file fashion along the length of said second nanotube,
- forming at least one nanojump within said second nanotube,
- wherein said nanojump comprises a localized region within said second nanotube wherein the average density of the substance particles within said nanojump differs from the average density of the substance particles in regions of similar size outside of said nanojump but within the second nanotube;
- and
- wherein the substance particles within said regions of similar size outside of said nanojump but within the second nanotube remain relatively stationary as substance particles within said nanojump region are transported along said second nanotube by said at least one nanojump;
- transporting a least a portion of said first substance from within the first nanotube by the passage of said at least one nanojump to a location outside of the first nanotube;
- and
- transporting at least a portion of said second substance from within the second nanotube by the passage of said at least one nanojump to a location outside of the second nanotube
- to facilitate a reaction at a location outside of said first nanotube and at a location outside of said second nanotube between at least a portion of said first substance and at least a portion of said second substance.
11 more elements
Dependencies are inferred from the claim text.