Dihydropyrene derivatives, processes for preparing the same and their uses

Compound of the following formula I (bis)

• wherein:
• n is 1,
• represents a single bond or no bond,
• represents a single or a double bond,
• R1 and R′1 represent independently from each other:
• H,
• a linear or branched (C1-C18)-alkyl,
• a (C3-C8)-cycloalkyl,
• —N(R)3+,
• R representing:
• H,
• a linear or branched (C1-C18)-alkyl,
• a (C3-C8)-cycloalkyl,
• R2, R3, R4 and R5 represent independently from each other:
• H,
• a linear or branched (C1-C18)-alkyl,
• a (C3-C8)-cycloalkyl,
• —N(R)3+,
• R representing:
• H,
• a linear or branched (C1-C18)-alkyl,
• a (C3-C8)-cycloalkyl,
• X represents one or more counter anion(s), in particular one or more physiologically acceptable counter anion(s),
• providing that:
• at least one of R1, R′1, R2, R3, R4 and R5 represents one of the following groups:
• or
• —N(R)3+f
• n, and the bonds 1 to 7 are such as:
• n=1, represents no bond, bonds 2, 5 and 7 represent a double bond, and bonds 1, 3, 4 and 6 represent a single bond.

A compound of the following formula I (bis)

• wherein:
• n represents 0 or 1,
• represents a single bond or no bond,
• represents a single or a double bond,
• R1 and R′1 represent independently from each other:
• H,
• a linear or branched (C1-C18)-alkyl,
• a (C3-C8)-cycloalkyl,
• —N(R)3+,
• R representing:
• H,
• a linear or branched (C1-C18)-alkyl,
• a (C3-C8)-cycloalkyl,
• R2, R3, R4 and R5 represent independently from each other:
• H,
• a linear or branched (C1-C18)-alkyl,
• a (C3-C8)-cycloalkyl,
• —N(R)3+,
• R representing:
• H,
• a linear or branched (C1-C18)-alkyl,
• a (C3-C8)-cycloalkyl,
• X represents one or more counter anion(s), in particular one or more physiologically acceptable counter anion(s),
• providing that:
• at least one of R1, R′1, R2, R3, R4 and R5 represents one of the following groups:
• or
• —N(R)3+,
• n, and the bonds 1 to 7 are such as:
• n=0, represents a single bond, bonds 1, 4 and 6 represent a double bond, and bonds 2, 3, 5 and 7 represent a single bond, or
• n=0, represents no bond, bonds 1, 3, 5 and 7 represent a double bond, and bonds 2, 4 and 6 represent a single bond, or
• n=1, represents no bond, bonds 2, 5 and 7 represent a double bond, and bonds 1, 3, 4 and 6 represent a single bond,
• when n=0, R1 and/or R′1 are different from one of the following groups:
• or
• —N(R)3+,
• wherein the compound of formula I(bis) forms a complex of the following formula II(bis)
• II (bis)
• B group being chosen from a peptide or an acid residue selected from a hyaluronic acid or a folic acid.