Uses of peptides to treat brain injury and disease
AssigneeCreative Bio-Peptides Inc.
InventorMichael Ruff
Life of this patent
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Abstract
A method of treating loss of brain function in a patient comprising the steps of preparing a composition comprising a D peptide and a pharmaceutically acceptable carrier. The D peptide has the general structure: A-B-C-D-E-F-G-H in which A is Ala, or absent, B is Ser, Thr or absent, C is Ser, Thr or absent, D is Ser, Thr, Asn, Glu, Arg, Ile, Leu, E is Ser, Thr, Asp, Asn, F is Thr, Ser, Asn, Arg, Gln, Lys, Trp, G is Tyr, and H is Thr, Ser, Arg, Gly. All amino acids in the D peptide are the D stereoisomeric configuration. The peptide composition is administered in a therapeutically effective dose.
Claims5
A method of treating brain trauma in a patient comprising the steps of:
- preparing a composition comprising a D peptide and a pharmaceutically acceptable carrier, said D peptide further comprises at most twenty (20) D amino acid residues in length and contains five contiguous D amino acid residues having the sequence Thr-Thr-Asn-Tyr-Thr (SEQ ID NO:
- 2), and administering said composition to the patient in a therapeutically effective dose, wherein said composition acts to treat the brain trauma in the patient, and wherein said brain trauma is traumatic brain injury.
Dependencies are inferred from the claim text.