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US 10,501,457 B2Granted
Compounds for bone growth
AssigneeOsteoQC Inc.
InventorsDebra Ellies, Jean-Philippe Rey, F. Scott Kimball
Life of this patent
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Abstract
In one aspect, the invention provides compounds of Formula I, and salts, hydrates and isomers thereof. In another aspect, the invention provides a method of promoting bone formation in a subject in need thereof by administering to the subject a therapeutically effective amount of a compound of Formula I, Formula II, or Formula III. The present invention also provides orthopedic and periodontal devices, as well as methods for the treatment of renal disease and cancer, using a compound of Formula I, Formula II, or Formula III.
Claims14
A compound having the formula:
- or a salt, or hydrate thereof;
- wherein
- R2 is selected from the group consisting of H, C1-6 alkoxy, —OH, and C1-6 alkyl-OH;
- R3a and R3b are independently selected from the group consisting of H, halo, C1-6 alkoxy, and —OH;
- R3d is selected from the group consisting of H, C1-6 alkyl and C1-6 haloalkyl;
- and
- the moiety
- is selected from the group consisting of:
5 more elements
Dependencies are inferred from the claim text.