Quinoxalinones and dihydroquinoxalinones as respiratory syncytial virus antiviral agents

A compound of formula I

• or a stereochemically isomeric or tautomeric form thereof wherein:
• Y is N or N—R4;
• Z1 is N or C—R6;
• Z2 is N or C—R3;
• R1 is selected from the group consisting of H, halogen, C1-C6alkyl and C3-C7cycloalkyl;
• R2 is —(CR7R8)n—R9;
• R3 is selected from the group consisting of H, C1-C6alkyl, C3-C7cycloalkyl, CF3 and halogen;
• R4 is selected from the group consisting of H, C1-C6alkyl and C3-C7cycloalkyl;
• R6 is selected from the group consisting of H, halogen, aryl and heteroaryl, wherein each of aryl or heteroaryl is optionally substituted with one or more R10;
• R7 and R8 are each independently selected from the group consisting of H, C1-C6alkyl and C3-C7cycloalkyl;
• n is an integer selected from the range of 1 to 6;
• R9 is selected from the group consisting of H, halogen, SO2R7, C1-C6alkyl, CONR7R8, COOR7, OH, CN, F, CFH2, CF2H and CF3;
• R10 is selected from the group consisting of H, OH, CN, halogen, CFH2, CF2H, CF3, CONR7R8, COOR7 and C1-C6 alkyl, wherein each of R10 is optionally substituted with one or more substituents selected from the group comprising NR7R8, CF3, CH3, OCH3, OCF3, morpholinyl and halogen;
• or an addition salt or solvate thereof.