Quinoline derivative
AssigneeOno Pharmaceuticals Co., Ltd.
InventorsTakayuki Inukai, Jun Takeuchi, Tomoko Yasuhiro
Life of this patent
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Abstract
A compound represented by general formula (I) has a strong Axl inhibitory activity by introducing a distinctive bicyclic structure in which a saturated carbon ring is fused to a pyridone ring, and can be a therapeutic agent for Axl-related diseases, for example, cancer such as acute myeloid leukemia, melanoma, breast cancer, pancreatic cancer, and glioma, kidney diseases, immune system diseases, and circulatory system diseases
Claims2
A pharmaceutical composition comprising a compound which is N-{5-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-pyridinyl}-2,5-dioxo-1-phenyl-1,2,5,6,7,8-hexahydro-3-quinolinecarboxamide, or a salt thereof;
- and a pharmaceutically acceptable carrier.
A pharmaceutical composition comprising a compound of the following chemical formula:
- and
- a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.