Neurostimulation titration process via adaptive parametric modification

A method of operating an implantable medical device (IMD) comprising a neurostimulator coupled to an electrode assembly, said method comprising:

• initiating a plurality of titration sessions, each titration session separated from an adjacent titration session by an acclimation interval, wherein the titration sessions comprise activating the IMD to deliver a stimulation signal of gradually increasing intensity until the patient exceeds a side effect tolerance zone boundary, wherein the stimulation signal comprises a frequency in a range of 5 Hz to 10 Hz;
• analyzing an outcome measure of the plurality of titration sessions;
• and
• modifying one or more stimulation parameters based on the analyzed outcome measure.

An implantable medical device comprising:

• an electrode assembly;
• a neurostimulator coupled to the electrode assembly, the neurostimulator configured to:
• initiate a plurality of titration sessions, each titration session separated from an adjacent titration session by an acclimation interval, wherein the titration sessions comprise activating the implantable medical device to deliver a stimulation signal of gradually increasing intensity until the patient exceeds a side effect tolerance zone boundary, wherein the stimulation signal comprises a frequency in a range of 5 Hz to 10 Hz;
• analyze an outcome measure of the plurality of titration sessions;
• and
• modify one or more stimulation parameters based on the analyzed outcome measure.