Systems and methods for fluid flows and/or pressures for circulation and perfusion enhancement

A method for adjusting fluid flow or pressure within a human body, the method comprising:

• transluminally inserting a pumping system for percutaneous delivery in a desired chamber or a desired vessel of the human body, wherein the pumping system comprises
• a first pump implantable in a chamber or vessel of the human body,
• a securing means extending from said first pump, wherein said securing means secures the first pump in a desired location of said chamber or vessel, and the securing means allows substantially unobstructed flow of blood around the first pump,
• one or more inlet ports disposed on said first pump, wherein said inlet ports direct inlet blood flow through the first pump, and bypass flow is directed around a pump housing, and
• one or more outlet ports disposed on said first pump, wherein said outlet ports direct at least one high-velocity jet of output blood flow from the first pump, and the output blood flow autoentrains the bypass blood flow to form downstream blood flow;
• deploying said securing means to secure said pumping system in a lumen of said desired chamber or said desired vessel, wherein the pumping system is deployed in a descending thoracic aorta superior to the celiac, renal, and mesenteric arteries, and the pumping system produces a pressure drop in an aortic root, reduces cardiac afterload, and increases cardiac output,
• wherein further the outlet ports are oriented to increase pressure or flow to at least one renal artery, and the one or more outlet ports of the first pump comprise
• a first outlet port directing a portion of the output blood flow to a first renal artery, and
• a second outlet port directing another portion of the output blood flow to a second renal artery;
• and
• operating the pumping system to cause the at least one high-velocity jet of the output blood flow to autoentrain the bypass blood flow.