Influenza virus vectors and uses therefor
AssigneeFluGen, Inc.
InventorsMatthew Frederick LeFebvre, Yasuko Hatta, Pamuk Bilsel, Michael J. Moser
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AssigneeFluGen, Inc.
InventorsMatthew Frederick LeFebvre, Yasuko Hatta, Pamuk Bilsel, Michael J. Moser
Estimating the term…
Disclosed herein are compositions and methods related to mutant viruses, and in particular, mutant influenza viruses. The mutant viruses disclosed herein include a mutant M2 sequence, and are useful in immunogenic compositions, e.g., as vaccines. The mutant viruses disclosed herein including a mutant M2 sequence are also useful to deliver antigens to a subject, e.g., to induce an immune response to the antigen. Also disclosed herein are methods, compositions and cells for propagating the viral mutants, and methods, devices and compositions related to vaccination.
An immunogenic composition comprising the nucleic acid sequence of SEQ ID NO:35, wherein SEQ ID NO:35 further comprises a nucleic acid sequence encoding one or more foreign antigens.
Dependencies are inferred from the claim text.