Compositions for delivery to and treatment of atherosclerotic plaques
AssigneeSanford Burnham Prebys Medical Discovery Institute
InventorsErkki Ruoslahti, Tambet Teesalu, Lauri Paasonen
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Abstract
Disclosed are compositions and methods for treatment of atherosclerosis and atherosclerotic plaques. In some forms, the compositions and methods can prevent, inhibit, or reduce atherosclerosis. In some forms, the compositions and methods can prevent, inhibit, or reduce atherosclerotic plaques. In particular, compositions comprising a plaque-homing element, a CendR-activating element, and a plaque-inhibiting element are disclosed.
Claims23
A composition comprising a plaque-homing element, a CendR-activating element, and a plaque-inhibiting element, wherein the plaque-homing element is CXaRGXbRSXcC (SEQ ID NO:3), wherein Xa and Xb, are independently are any amino acid, and, independently, Xc is any amino acid or is absent.
Dependencies are inferred from the claim text.