Topical compositions
AssigneeNovan, Inc.
InventorsRyan Doxey, Nathan Stasko
Life of this patent
Estimating the term…
Abstract
Provided herein are anhydrous compositions that include at least one viscosity increasing agent, at least one organic solvent and at least one humectant. Such compositions may also include at least one active pharmaceutical ingredient (API) and/or at least one water repellant. Related compositions, methods and kits are also provided.
Claims28
A method of decreasing abnormal keratinization, reducing microbial colonization, reducing inflammation and/or decreasing sebum production in a subject in need thereof, the method comprising applying an anhydrous composition to the skin of a subject to treat the dermatological condition,
- wherein the anhydrous composition consists essentially of:
- hydroxypropyl cellulose at a concentration in a range of 0.5% to about 2% by weight of the anhydrous composition,
- ethanol or isopropyl alcohol at a concentration in a range of 45% to 90% by weight of the anhydrous composition,
- hexylene glycol at a concentration of about 10% by weight of the anhydrous composition,
- cyclomethicone at a concentration of about 2.5% by weight of the anhydrous composition, and
- a nitric oxide (NO)-releasing compound at a concentration in a range of 0.01% to 40% by weight of the anhydrous composition,
- wherein the method decreases abnormal keratinization, microbial colonization, inflammation, and/or sebum production in the skin of the subject.
A method of treating a dermatological condition, the method comprising applying an anhydrous composition to the skin of a subject to treat the dermatological condition,
- wherein the anhydrous composition consists essentially of:
- hydroxypropyl cellulose at a concentration in a range of 0.5% to about 2% by weight of the anhydrous composition,
- ethanol or isopropyl alcohol at a concentration in a range of 45% to 90% by weight of the anhydrous composition,
- hexylene glycol at a concentration of about 10% by weight of the anhydrous composition,
- cyclomethicone at a concentration of about 2.5% by weight of the anhydrous composition, and
- a nitric oxide (NO)-releasing compound at a concentration in a range of 0.01% to 40% by weight of the anhydrous composition,
- wherein the dermatological condition comprises acne, a scar, a wound, and/or a biofilm.
Dependencies are inferred from the claim text.