Back to results
US 10,500,202 B2Granted
Pharmaceutical formulation containing tadalafil
AssigneeDruggability Technologies IP Holdco Limited
InventorsBetti Szabóné Ordasi, Tamás Jordán, Richárd Balázs Kárpáti, Andrea Ujhelyi, Tamás Solymosi, Hristos Glavinas, Genovéva Filipcsei
Life of this patent
Estimating the term…
Abstract
Disclosed herein are pharmaceutical compositions comprising Tadalafil, or a salt, or derivatives thereof and pharmaceutical excipients, processes for the preparation thereof, and pharmaceutical compositions containing them. The pharmaceutical compositions have improved physicochemical properties that provide faster onset of action for the treatment of erectile dysfunction.
Claims9
A pharmaceutical composition comprising
- 10-40% by weight of Tadalafil or a salt thereof;
- 35-70% by weight of a primary pharmaceutical excipient which is copovidone (copolymer of vinylpyrrolidone and vinyl acetate);
- and
- 5-50% by weight of a secondary pharmaceutical excipient which is sodium lauryl sulfate;
- wherein said pharmaceutical composition is obtained by a process comprising mixing followed by spray-drying;
- wherein said pharmaceutical composition has a controlled particle size in the range between 10 nm and 500 nm;
- and
- wherein said pharmaceutical composition shows X-ray amorphous character in the solid form.
5 more elements
Dependencies are inferred from the claim text.