Method for enhancing energy production and metabolism in cells

A method of treating a non-communicable disease or disorder the method comprising administering a composition comprising one or more compounds selected from the group consisting of D-glyceric acid, DL-glyceric acid, L-glyceric acid, a salt of D-glyceric acid, a salt of DL-glyceric acid, an ester of D-glyceric acid, and an ester of DL-glyceric acid, wherein the salts of D-glyceric acid and DL-glyceric acid are calcium salts, as the only active substance or substances, to a subject in need thereof, wherein the composition enhances mitochondrial ATP production and simultaneously reduces excessive radical oxygen species formation from oxidative phosphorylation (OXPHOS), and wherein the non-communicable disease or disorder is selected from the group consisting of:

• a cardiovascular disease or disorder, mitochondrial DNA depletion, mitochondrial diseases, cerebrovascular accident, damage from acute head injury, acute or chronic renal failure, acute or chronic liver failure, splenomegaly, acute or chronic pancreatic failure, hemorrhagic shock, pre-eclampsia, thyroid disease, chronic fatigue, fibromyalgia, multi-organ dysfunction syndrome, epilepsy, bipolar disorder, psychiatric and mood disorders, cancer, obesity, high blood pressure, an age-related degeneration disease or disorder, rheumatoid arthritis, gout, and chronic obstructive pulmonary disease.

A method of treating a non-communicable disease or disorder the method comprising administering a composition comprising one or more compounds selected from the group consisting of D-glyceric acid, DL-glyceric acid, L-glyceric acid, and salts and esters thereof, as the only active substance or substances, to a subject in need thereof, wherein the composition enhances mitochondrial ATP production and simultaneously reduces excessive radical oxygen species formation from oxidative phosphorylation (OXPHOS), and wherein the non-communicable disease or disorder is selected from the group consisting of:

• a cardiovascular disease or disorder, mitochondrial DNA depletion, mitochondrial diseases, cerebrovascular accident, damage from acute head injury, acute or chronic renal failure, acute or chronic liver failure, splenomegaly, acute or chronic pancreatic failure, hemorrhagic shock, pre-eclampsia, thyroid disease, chronic fatigue, fibromyalgia, multi-organ dysfunction syndrome, bipolar disorder, psychiatric and mood disorders, obesity, high blood pressure, an age-related degeneration disease or disorder, rheumatoid arthritis, gout, and chronic obstructive pulmonary disease.