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US 10,500,139 B2Granted
Formulations and materials with cationic polymers
AssigneeUCL Business PLC
InventorAnne Margaret Young
Life of this patent
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Abstract
This invention provides fluid formulations and materials produced therefrom for repairing dental and bone defects, processes for the production of the fluid formulations and materials, and to uses of these formulations and materials. In particular, the invention provides the use cationic polymers such as polylysine in these formulations and materials, and the advantageous properties derived therefrom which include mechanical and antibacterial properties.
Claims20
A process for production of a material which is a composite or a compomer, the process comprising the steps of:
- i) providing a fluid formulation comprising:
- (1) a fluid phase containing no water comprising at least one base monomeric or oligomeric hydrophobic compound capable of polymerisation and optionally cross-linking, which comprises a polymerisable methacrylate moiety,
- (2) a filler which comprises:
- (a) a reactive component comprising at least one calcium-containing compound, and
- (b) a glass powder or silane-treated glass powder, and
- (c) a cationic polymer, which is polylysine, present in the filler as solid particles;
- and
- ii) covalently polymerising and optionally cross-linking said base monomeric or oligomeric compound via the methacrylate moiety, thereby forming a solid polymer matrix comprising the particles of cationic polymer.
5 more elements
Dependencies are inferred from the claim text.