Method, storage medium, and system for analyzing image sequences of periodic physiological activities

A non-transitory computer-readable storage medium, with computer-executable instructions stored thereon, wherein the instructions, when executed by a processor, cause the processor to perform a method for analyzing an image sequence of a periodic physiological activity, the method comprising:

• receiving the image sequence acquired by an imaging device, the image sequence having a plurality of frames;
• determining local motions for pixels in each frame of the image sequence, wherein the local motion for a pixel is determined using corresponding pixels in frames adjacent to the frame to which the pixel belongs;
• determining principal motions for the plurality of frames based on the local motions;
• determining a motion magnitude profile based on the principal motions;
• and
• determining the phase of each frame in the image sequence based on the motion magnitude profile.

A system for performing analysis on an image sequence of periodic physiological activity, comprising:

• a processor;
• and
• a memory storing computer-executable instructions that, when executed by the processor, cause the processor to:
• receive the image sequence acquired by an imaging device, the image sequence having a plurality of frames;
• determine local motions for pixels in each frame of the image sequence, wherein the local motion for a pixel is determined using corresponding pixels in frames adjacent to the frame to which the pixel belongs;
• determine principal motions for the plurality of frames based on the local motions;
• determine a motion magnitude profile based on the principal motions;
• and
• determine the phase of each frame in the image sequence based on the motion magnitude profile.