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US 10,482,605 B2Granted
Cell area determination method, cell imaging system, and cell image processing apparatus
AssigneesSysmex Corporation, National University Corporation Tokyo Medical and Dental University
InventorsKazumi Hakamada, Yuki Aihara, Masaya Okada, Toshiyuki Sato, Ichiro Sekiya, Eiji Kobayashi
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Abstract
A method comprises obtaining a first cell image of a cell by a first observation method, obtaining a second cell image of the cell by a second observation method that is different from the first observation method, and determining the region of the cell based on the first cell image and the second cell image.
Claims18
A method comprising:
- obtaining a first cell image of a cell by a first observation method;
- obtaining a second cell image of the cell by a second observation method that is different from the first observation method;
- and
- determining a region of the cell based on the first cell image and the second cell image, wherein determining the region of the cell further comprises:
- determining a first cell region in the first cell image based on the first cell image;
- determining a second cell region in the second cell image based on the second cell image;
- generating a composite image by overlaying the first cell region and the second cell region;
- identifying a first noise region included in the first cell region based on the size of the region, and performing a first noise removal process to remove the first noise region from the first cell region;
- and
- identifying a second noise region included in the second cell region based on the size of the region, and performing a second noise removal process to remove the second noise region from the second cell region;
- the first cell region used to generate the composite image is a first cell region from which the first noise region has been removed;
- and
- the second cell region used to generate the composite image is a second cell region from which the second noise region has been removed.
10 more elements
A cell imaging system, comprising:
- an imaging part configured to generate a first cell image by imaging a cell using a first observation method, and generate a second cell image by imaging the cell using a second observation method that is different from the first observation method;
- and
- a processing part configured to execute image processing,
- wherein the image processing comprises:
- obtaining the first cell image from the imaging part;
- obtaining the second cell image from the imaging part;
- and
- determining a region of the cell based on the first cell image and the second cell image, wherein determining the region of the cell further comprises:
- determining a first cell region in the first cell image based on the first cell image;
- determining a second cell region in the second cell image based on the second cell image;
- generating a composite image by overlaying the first cell region and the second cell region;
- identifying a first noise region included in the first cell region based on the size of the region, and performing a first noise removal process to remove the first noise region from the first cell region;
- and
- identifying a second noise region included in the second cell region based on the size of the region, and performing a second noise removal process to remove the second noise region from the second cell region;
- the first cell region used to generate the composite image is a first cell region from which the first noise region has been removed;
- and
- the second cell region used to generate the composite image is a second cell region from which the second noise region has been removed.
14 more elements
A processing apparatus comprising a processing part configured to execute processes of:
- obtaining a first cell image of a cell by a first observation method;
- obtaining a second cell image of the cell by a second observation method that is different from the first observation method;
- and
- determining a region of the cell based on the first cell image and the second cell image, wherein determining the region of the cell further comprises:
- determining a first cell region in the first cell image based on the first cell image;
- determining a second cell region in the second cell image based on the second cell image;
- generating a composite image by overlaying the first cell region and the second cell region;
- identifying a first noise region included in the first cell region based on the size of the region, and performing a first noise removal process to remove the first noise region from the first cell region;
- and
- identifying a second noise region included in the second cell region based on the size of the region, and performing a second noise removal process to remove the second noise region from the second cell region;
- the first cell region used to generate the composite image is a first cell region from which the first noise region has been removed;
- and
- the second cell region used to generate the composite image is a second cell region from which the second noise region has been removed.
10 more elements
Dependencies are inferred from the claim text.