Separation devices and sensors including two dimensional materials that change properties when exposed to components separated from a sample

A microchip detection and separation device configured to separate and detect multiple individual components in a sample, the microchip comprising:

• a separation device having at least one inlet configured to receive the sample and at least one outlet configured to permit the outflow of the multiple individual components of the sample, and channels between the inlet and the outlet, the channels having at least one diameter in the range of from about one micron to about one millimeter;
• and
• at least one sensor configured to detect at least one of the multiple individual components of the sample when at least one of the individual multiple components is volatilized or is a liquid, the sensor including at least one channel formed in at least one material selected from the group consisting of a two dimensional material, a substantially two dimensional material and combinations thereof, the sensor having a sensing property which changes at least 3% when the material is exposed to a component forming not more than about one pico gram of the sample, and the material is configured to detect multiple individual components of the sample and is capable of detecting at least one of the individual components which form not more than about 1 pico gram of the sample.