Mass spectrometer and biological sample analysis method using said mass spectrometer

A mass analysis device which comprises, as an ion source, a conductive probe, a high voltage generation unit which applies a high voltage to said probe, and a displacement unit which causes at least one of either said probe, which is arranged extending in the vertical direction, or a sample arranged below the probe, to move vertically so as to cause the sample to adhere to the tip of said probe, wherein components in the sample are ionized under atmospheric pressure utilizing the electrospray phenomenon, by applying a high voltage to said probe by means of said high voltage generation unit after a portion of the sample has been caused to adhere to the tip of said probe by means of said displacement unit,

• the mass analysis device being characterized in that it comprises a solvent supply unit which is arranged at a position which is above the sample and through which the tip of said probe passes when at least one of either the probe or the sample is moved by said displacement unit, said solvent supply unit comprising:
• a) a container unit which holds solvent inside and which has an aperture in its top surface and bottom surface, through which said probe can be inserted in the direction of its extension, and has a liquid-impervious first membrane member provided so as to occlude the aperture in the bottom surface;
• and
• b) a second liquid-impervious membrane member which is provided on the outside of said container unit at a predetermined gap from said first membrane member and whereof the bottom surface contacts the top surface of the sample when the solvent supply unit is arranged over the sample.