Osteochondroreticular stem cells for bone and cartilage regeneration
AssigneeThe Trustees of Columbia University in the City of New York
InventorsTimothy Wang, Daniel Worthley, Siddhartha Mukherjee
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Abstract
The invention is directed to osteochondroreticular stem cells and methods of using osteochondroreticular stem cells. In another aspect the invention is directed to a method of treating osteoarthritis or skeletal fractures using osteochondroreticular stem cells.
Claims4
A method of treating a disease, degeneration, or injury of bone, or cartilage, or both, in a subject comprising administering a therapeutically effective amount of a composition comprising an acceptable carrier and isolated osteochondroreticular (OCR) stem cells that express Grem1 to a site in need thereof in the subject, wherein the isolated OCR stem cells are at least about 70% pure.
Dependencies are inferred from the claim text.