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US 10,479,834 B2Granted
Fc receptor antibodies and methods of use thereof
AssigneeDyax Corp.
InventorsDaniel J. Sexton, Christopher TenHoor, Malini Viswanathan
Life of this patent
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Abstract
The disclosure relates to antibodies that bind FcRn and methods of using these antibodies.
Claims16
An isolated anti-neonatal Fc receptor (FcRn) antibody comprising a light chain variable region (VL) and a heavy chain variable region (VH), wherein the antibody binds to human FcRn;
- wherein the VL comprises:
- (i) a VL CDR1 comprising the amino acid sequence of SEQ ID NO:14;
- (ii) a VL CDR2 comprising the amino acid sequence of SEQ ID NO:15;
- and
- (iii) a VL CDR3 comprising the amino acid sequence of SEQ ID NO:12 or SEQ ID NO:13;
- and
- wherein the VH comprises:
- (i) a VH CDR1 comprising the amino acid sequence of SEQ ID NO:22;
- (ii) a VH CDR2 comprising the amino acid sequence of SEQ ID NO:23;
- and
- (iii) a VH CDR3 comprising the amino acid sequence of SEQ ID NO:24.
8 more elements
Dependencies are inferred from the claim text.