GARP-TGF-beta 1 antibodies

A recombinant antibody or antigen binding fragment thereof, which binds to a complex of human glycoprotein A repetitions predominant (GARP) and TGF-β1, wherein the antibody or antigen binding fragment thereof comprises

• a heavy chain variable domain (VH), wherein:
• the VH CDR3 comprises the amino acid sequence YEWETVVVGDLMYEYEY (SEQ ID NO:
• 13),
• the VH CDR2 comprises the amino acid sequence RIDPEDAGTKYAQKFQG (SEQ ID NO:
• 12), and
• the VH CDR1 comprises the amino acid sequence SYYID (SEQ ID NO:
• 4);
• and
• a light chain variable domain (VL), wherein:
• the VL CDR3 comprises the amino acid sequence QQYASVPVT (SEQ ID NO:
• 11),
• the VL CDR2 comprises the amino acid sequence GASRLKT (SEQ ID NO:
• 10), and
• the VL CDR1 comprises the amino acid sequence QASQSISSYLA (SEQ ID NO:
• 9).