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US 10,479,825 B2Granted
Antibody-mediated neutralization of Marburg virus
AssigneesVanderbilt University, Board of Regents, The University of Texas System
InventorsJames E. Crowe, Andrew I. Flyak, Alexander Bukreyev, Philipp Ilinykh
Life of this patent
Estimating the term…
Abstract
The present disclosure is directed to antibodies binding to Marburg virus (MARV) glycoprotein (GP) and methods of use therefore.
Claims24
An engineered cell producing an antibody or antibody fragment characterized by heavy chain CDR sequences of SEQ ID NOS:
- 104, 105 and 106 and light chain CDR sequences of SEQ ID NO:
- 150, DNN and SEQ ID NO:
- 151.
A method of inhibiting a Marburg virus or Ebola virus in a subject comprising delivery to said subject an antibody or antibody fragment having heavy chain CDR sequences of SEQ ID NOS:
- 104, 105 and 106 and light chain CDR sequences of SEQ ID NO:
- 150, DNN and SEQ ID NO:
- 151.
Dependencies are inferred from the claim text.