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US 10,478,822 B1Granted
Automated cell processing instruments comprising reagent cartridges
AssigneeInscripta, Inc.
InventorsDon Masquelier, Phillip Belgrader, Brian Van Hatten, Jorge Bernate, Bruce Chabansky
Life of this patent
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Abstract
The present disclosure provides a reagent cartridge configured for use in an automated multi-module cell processing environment.
Claims20
An automated multi-module cell processing instrument comprising:
- a housing;
- a reagent cartridge, wherein the reagent cartridge comprises:
- a thermal block with block reservoirs defined therein;
- a cover disposed upon the thermal block with cover reservoirs defined therein, wherein the cover reservoirs and block reservoirs are coincident and together define reservoirs in the reagent cartridge;
- an insert comprising a transformation module, wherein the transformation module is a flow-through electroporation device;
- a script readable by a processor;
- at least two additional inserts configured to reside within the reservoirs in the reagent cartridge;
- and
- reagents dispensed in one or more of the reservoirs;
- a growth module;
- a cell concentration module;
- an editing module;
- and
- the processor.
11 more elements
An automated multi-module cell processing instrument comprising:
- a housing;
- a reagent cartridge for an automated multi-module cell processing instrument, wherein the reagent cartridge comprises:
- a thermal block with block reservoirs defined therein;
- a cover disposed upon the thermal block with cover reservoirs defined therein, wherein the cover reservoirs and block reservoirs are coincident and together define reservoirs in the reagent cartridge;
- an insert comprising a transformation module;
- a script readable by a processor;
- at least two additional inserts configured to reside within the reservoirs in the reagent cartridge;
- and
- reagents dispensed in one or more of the reservoirs;
- a growth module;
- a cell concentration module;
- a singulation and editing module;
- and
- the processor.
11 more elements
An automated multi-module cell processing instrument comprising:
- a housing;
- a reagent cartridge for an automated multi-module cell processing instrument, wherein the reagent cartridge comprises:
- a thermal block with block reservoirs defined therein;
- a cover disposed upon the thermal block with cover reservoirs defined therein, wherein the cover reservoirs and block reservoirs are coincident and together define reservoirs in the reagent cartridge;
- an insert comprising a transformation module;
- a script readable by a processor;
- at least two additional inserts configured to reside within the reservoirs in the reagent cartridge;
- and
- reagents dispensed in one or more of the reservoirs;
- a growth module;
- a cell concentration module;
- and
- the processor.
10 more elements
Dependencies are inferred from the claim text.