Personalized parameter modeling methods and related devices and systems

A method of operating a sensing device associated with a patient, the sensing device including a control module coupled to a sensing element configured to measure a physiological condition in a body of the patient, the method comprising:

• obtaining, by the control module of the sensing device, current operational context information associated with the sensing device;
• obtaining, by the control module, an expected calibration factor parameter model associated with the patient;
• calculating, by the control module, an expected calibration factor value based on the expected calibration factor parameter model and the current operational context information;
• obtaining, by the control module, one or more electrical signals from the sensing element of the sensing device, the one or more electrical signals having a signal characteristic indicative of the physiological condition in the body of the patient;
• converting, by the control module, the one or more electrical signals into a calibrated measurement value for the physiological condition in the body of the patient using the expected calibration factor value;
• and
• outputting, by the control module, the calibrated measurement value for the physiological condition in the body of the patient.