Probability based controller gain

An apparatus for estimating a glucose level of a person having diabetes and selecting automatically open-loop and closed-loop control for a connected therapy delivery device, the apparatus comprising a microcontroller and a display, wherein:

• the microcontroller is configured to:
• receive a plurality of measured glucose results and corresponding impedance values from a glucose sensor coupled to the person,
• analyze the plurality of measured glucose results and corresponding impedance values with a probability analysis tool configured to determine a total quality score Qtotal that is based on the minimum constraint of a set of quality metrics which comprises a probability of glucose sensor accuracy PA based on the plurality of measured glucose results and a probability of sensing quality Qac based on the impedance values,
• estimate the glucose level of the person with a recursive filter configured to estimate the glucose level based on the plurality of measured glucose results weighted with the total quality score Qtotal,
• switch the connected therapy delivery device automatically between open-loop control and closed-loop control based on the value of the total quality score Qtotal, and
• transmit to the display information related to the estimate of the glucose level of the person and the control switch of the therapy delivery device.

A method for estimating glucose level of a person having diabetes, the method comprising:

• collecting, via a blood glucose management device having a microcontroller, a plurality of measured glucose results and corresponding impedance values from a glucose sensor coupled to the person;
• using the microcontroller to analyze the plurality of measured glucose results and corresponding impedance values with a probability analysis tool configured to determine a total quality score Qtotal that is based on the minimum constraint of a set of quality metrics which comprises a probability of glucose sensor accuracy PA based on the plurality of measured glucose results and a probability of sensing quality Qac based on the impedance values;
• using the microcontroller to estimate the glucose level of the person with a recursive filter configured to estimate the glucose level based on the plurality of measured glucose results weighted with the total quality score Qtotal;
• and
• alerting via the microcontroller updating a display of the management device with a warning upon the estimated glucose level of the person being one of hypoglycemic and hyperglycemic.

An apparatus for estimating a glucose level of a person having diabetes, the apparatus comprising a microcontroller and a display, wherein:

• the microcontroller is configured to:
• collect a plurality of measured glucose results and corresponding impedance values from a glucose sensor coupled to the person,
• analyze the plurality of measured glucose results and corresponding impedance values with a probability analysis tool configured to determine a total quality score Qtotal that is based on the minimum constraint of a set of quality metrics which comprises a probability of glucose sensor accuracy PA based on the plurality of measured glucose results and a probability of sensing quality Qac based on the impedance values,
• estimate the glucose level of the person with a recursive filter configured to estimate the glucose level based on the plurality of measured glucose results weighted with the total quality score Qtotal,
• transmit to the display information related to the estimate of the glucose level of the person, and
• alert via the display with a warning upon the estimated glucose level of the person being one of hypoglycemic and hyperglycemic.