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US 10,478,528 B2Granted
Bone graft implants containing allograft
AssigneeProsidyan, Inc.
InventorsCharanpreet S. Bagga, Steven B. Jung, Hyun W. Bae
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Abstract
Synthetic, bioactive ultra-porous bone graft materials having an engineered porosity, and implants formed from such materials are provided. In particular, these implants comprise bioactive glass and incorporate allograft material for osteoinduction. The implants are suitable for bone tissue regeneration and/or repair.
Claims9
A porous, composite bone graft implant comprising:
- a first component comprising a bioactive glass material in the form of a plurality of bioactive glass clusters, each cluster comprising a matrix of randomly oriented bioactive glass fibers and bioactive glass granules, at least some of the fibers and granules being sintered together, the clusters further including a bioactive glass shell at least partially encasing the matrix;
- a second component comprising an allograft material, the second component being interspersed with the first component throughout the composite bone graft implant;
- and
- a third component comprising a polymeric coating extending over the implant;
- wherein the composite implant comprises a pore size distribution including at least a nanoporosity, and wherein the composite implant is pliable.
2 more elements
Dependencies are inferred from the claim text.