Use of von Willebrand factor
AssigneesLaboratoire Francais Du Fractionnement Et Des Biotechnologies, CTRE Hospitalier Universitaire de Lille, Universite Lille 2 Droit Et Sante
InventorsSophie Susen, Andre Vincentelli, Eric Van Belle, Antoine Rauch, Flavien Vincent
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Abstract
The present invention relates to a von Willebrand factor composition for the prevention and/or the treatment of haemorrhage and/or bleeding in patients with mechanical circulatory support.
Claims12
A method of treating or preventing haemorrhage and/or bleeding in patients with mechanical circulatory support, comprising administering to the patient a pharmaceutical composition comprising von Willebrand factor in an amount effective for treating or preventing haemorrhage and/or bleeding in patients with mechanical circulatory support, wherein the composition contains a residual amount of factor VIII less than or equal to 10 IU/100 IU VWF:RCo, and wherein the composition is administered to the patient at a dose of 45 IU/kg to 55 IU/kg of body weight.
Dependencies are inferred from the claim text.