Electroporation ablation apparatus, system, and method

An ablation system for mounting to a flexible shaft, the ablation system comprising:

• a first probe configured to extend through a first longitudinal lumen defined in the flexible shaft, the first probe comprising:
• a distal end positioned external to the flexible shaft;
• and
• a proximal end, wherein a first bore is defined by the first probe between the distal end and the proximal end of the first probe along a first axis, and wherein the proximal end of the first probe is configured for communication with a suction source to extract tissue through the first bore;
• a first electrode coupled to the distal end of the first probe external to the flexible shaft;
• a first conductor electrically coupled to the first electrode;
• a second probe configured to extend through a second longitudinal lumen defined in the flexible shaft, the second probe comprising:
• a distal end positioned external to the flexible shaft;
• and
• a proximal end, wherein a second bore is defined in the second probe between the distal end and the proximal end of the second probe along a second axis, and wherein the proximal end of the second probe is configured for communication with the suction source to extract tissue through the second bore;
• a second electrode coupled to the distal end of the second probe external to the flexible shaft;
• and
• a second conductor electrically coupled to the second electrode;
• wherein the first probe and the second probe are rotatable about and translatable along the first axis and the second axis respectively, and wherein the first electrode and the second electrode are rotatably and translatably positionable with respect to one another, via the first probe and the second probe, to define a region between the first electrode and the second electrode.

An ablation device mountable on an elongate shaft that defines a first lumen and a second lumen, wherein the ablation device comprises:

• a first probe configured to extend through the first lumen, wherein the first probe comprises:
• a distal portion located external to a distal end of the elongate shaft;
• and
• a proximal portion, wherein a first bore is defined by the first probe from the proximal portion to the distal portion of the first probe, and wherein the proximal portion of the first probe is attachable to a suction source to extract tissue through the first bore;
• a first electrode attached to an external surface of the distal portion of the first probe;
• a first conductor electrically coupled to the first electrode;
• a second probe configured to extend through the second lumen, wherein the second probe comprises:
• a distal portion located external to the distal end of the elongate shaft;
• and
• a proximal portion, wherein a second bore is defined by the second probe from the proximal portion to the distal portion of the second probe, and wherein the proximal portion of the second probe is attachable to the suction source to extract tissue through the second bore;
• a second electrode attached to an external surface of the distal portion of the second probe;
• and
• a second conductor electrically coupled to the second electrode;
• wherein the first probe and the second probe are rotatable and translatable relative to the first lumen and the second lumen respectively, and wherein the first electrode and the second electrode are rotatably and translatably positionable with respect to one another, via the first probe and the second probe, to define a region between the first electrode and the second electrode.