Space-efficient containment devices and method of making same

A containment device comprising:

• a first microchip element which comprises a containment reservoir that can be electrically activated to open;
• a first electronic printed circuit board (PCB) which comprises a biocompatible substrate, wherein the first PCB has a first side on which one or more electronic components are fixed and an opposed second side on which the first microchip element is fixed in electrical connection to the one or more electronic components;
• a second electronic printed circuit board (PCB) which comprises a biocompatible substrate, wherein the second PCB has a first side on which one or more electronic components are fixed and an opposed second side;
• and
• a housing ring securing the first PCB together with the second PCB,
• wherein the first side of the first PCB is oriented in a facing relationship toward the first side of the second PCB.

An implantable medical device comprising:

• a first microchip element which comprises an array of containment reservoirs which are configured to be opened independently in vivo to release s drug contained in the containment reservoirs or to expose sensors contained in the containment reservoirs;
• a first electronic printed circuit board (PCB) which comprises an alumina substrate, wherein the first PCB has a first side on which one or more electronic components are fixed and an opposed second side on which the first microchip element is fixed in electrical connection to the one or more electronic components;
• a second electronic printed circuit board (PCB) which comprises an alumina substrate;
• and
• a titanium housing ring securing the first PCB together with the second PCB,
• wherein the first PCB, the second PCB, and the housing ring form a hermetic enclosure about the one or more electronic components.