Methods and devices for three-dimensional printing or additive manufacturing of bioactive medical devices
AssigneeLouisiana Tech Research Corporation
InventorsJeffery Adam Weisman, Connor Nicholson, David Mills
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Abstract
A method for manufacturing a bioactive implant including the steps of (a) forming a mixture of an bioactive agent and a setting agent capable of transitioning from a flowable state to a rigid state; (b) converting the mixture into a flowable state; and (c) transitioning the mixture into a solid state in a shape of the implant.
Claims19
A method for manufacturing a bioactive implant comprising the steps of:
- a. forming a mixture of at least one of an antimicrobial, an antiseptic, or a chemo-therapeutic with a polymer stock material, wherein (i) the antimicrobial, antiseptic, or chemo-therapeutic ranges from about 0.01% to about 75% by weight of the mixture, and (ii) the mixture further comprises an adhering agent enhancing the adhesion of the bioactive agent to the polymer stock material, the adhering agent being at least one from the group consisting of biological oils, silicone-based substances, and water;
- b. heating the mixture to an approximate meltflow temperature of the polymer stock material;
- and
- c. forming the mixture into a shape of a stent or a catheter using 3D printing.
A method for manufacturing a bioactive implant comprising the steps of:
- a. forming a mixture of at least one of an antimicrobial, an antiseptic, or a chemo-therapeutic with a polymer stock material, wherein (i) the antimicrobial, antiseptic, or chemo-therapeutic ranges from about 0.01% to about 75% by weight of the mixture, and (ii) the mixture further includes nanostructures from the group consisting of carbone, grapheme, halloysite, titanium, zinc nanotubes and oxidized forms thereof;
- b. heating the mixture to an approximate meltflow temperature of the polymer stock material;
- and
- c. forming the mixture into a shape of a stent or a catheter using 3D printing.
A method for manufacturing a bioactive implant comprising the steps of:
- a. forming a mixture of at least one of an antimicrobial, an antiseptic, or a chemo-therapeutic with a polymer stock material;
- b. heating the mixture to an approximate meltflow temperature of the polymer stock material;
- c. forming the mixture into a shape of a stent or a catheter using 3D printing;
- and
- d. wherein the mixture further includes at least one mineral from the group consisting of magnesium dioxide, zinc oxide, titanium dioxide, and clay nanoparticles.
A method for manufacturing a bioactive implant comprising the steps of:
- a. forming a mixture of at least one of an antimicrobial, an antiseptic, or a chemo-therapeutic with a polymer stock material, wherein the antimicrobial, antiseptic, or chemo-therapeutic ranges from about 0.01% to about 75% by weight of the mixture;
- b. heating the mixture to an approximate meltflow temperature of the polymer stock material;
- and
- c. forming the mixture into a shape of a stent or a catheter using 3D printing, wherein the printing step includes printing a honeycombed structure having a void content of at least 5%.
Dependencies are inferred from the claim text.