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US 10,441,644 B2Granted
H3.3 CTL peptides and uses thereof
AssigneeThe Regents of the University of California
InventorsHideho Okada, Yafei Hou
Life of this patent
Estimating the term…
Abstract
Peptides that generate an immune response to glioma-related H3.3 proteins and methods of their use are provided.
Claims4
A T-cell expressing one or more polypeptides comprising a T-cell receptor (TCR) or fragment thereof that binds to a peptide/major histocompatibility complex (MHC) complex, wherein the peptide in the peptide/MHC complex consists of 10-12 amino acids and comprises (R/A)MSAP(S/A)TGGV (SEQ ID NO:1).
Dependencies are inferred from the claim text.