Oligodeoxy nucleotide for preparing drugs for inhibiting tumor growth and application thereof
AssigneesJiangsu Keygen Biotech Corp., Ltd, Nanjing New Industry Investment Group Co., Ltd
InventorsXuegen Wang, Qing Ye, Yijun Sun
Life of this patent
Estimating the term…
Abstract
The present invention provides an oligodeoxy nucleotide for preparing drugs for inhibiting tumor growth and an application thereof. The core sequences of the oligodeoxy nucleotide is TTTCSCGCS, wherein S is C or G. The oligodeoxy nucleotide above further comprises an antisense strand and a modified type thereof. The oligodeoxy nucleotide according to the present invention plays a role of inhibiting the tumor growth in vitro and vivo, and is expected to be used for preparing drugs for inhibiting tumor growth, with high specificity and high inhibition ratio.
Claims17
An oligodeoxy nucleotide for preparing drugs for inhibiting tumor growth, wherein the oligodeoxy nucleotide is any one of the following sequences:
- (SEQ ID NO:
- 7)
- 5′-TGACTATTTCCCGCGACTT-3′;
- (SEQ ID NO:
- 8)
- 5′-TTGACTATTTCCCGCCACTT-3′;
- and
- (SEQ ID NO:
- 9)
- 5′-ATCTATTTCGCGCCCTTATG-3′.
An oligodeoxy nucleotide for preparing drugs for inhibiting tumor growth, wherein a sequence of the oligodeoxy nucleotide consists of the following sequence:
- (SEQ ID NO:
- 10)
- 5′-TTAAGTTTCGCGCCCTTTCTC-3′.
Dependencies are inferred from the claim text.