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US 10,441,579 B2Granted
4-[2-(2-fluorophenoxymethyl)phenyl]piperidine compounds
AssigneeTheravance Biopharma R&D IP, LLC
InventorsLori Jean Patterson, Eric L. Stangeland
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Abstract
The invention relates to compounds of formula I: where a, R1, and R3-6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. The compounds of formula I are serotonin and norepinephrine reuptake inhibitors. The invention also relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.
Claims9
A pharmaceutical composition comprising:
- (a) a compound of the formula:
- or a pharmaceutically acceptable salt thereof;
- and
- (b) a pharmaceutically acceptable carrier selected from starch, microcrystalline cellulose, lactose, sucrose, glucose, mannitol, silicic acid and mixtures thereof.
1 more element
Dependencies are inferred from the claim text.