US 10,441,558 B2Granted

Therapeutic approaches for treating CMT and related disorders

AssigneePharnext

InventorsDaniel Cohen, Ilya Chumakov, Oxana Guerassimenko, Serguei Nabirochkin

Life of this patent

Estimating the term…

Abstract

Compositions and methods for the treatment of Charcot-Marie-Tooth disease and related disorders. Also provided are combination therapies for treating this disease by decreasing PMP22 expression in a subject.

Claims9

Dependent claims

A method for treating Charcot-Marie-Tooth (CMT) disease of type 1 A (CMT1A), comprising administering to a subject in need thereof an effective amount of baclofen, or a salt thereof or a sustained release formulation thereof.

Dependencies are inferred from the claim text.

Facts

Application: 16/055,710Filed 6 Aug 2018 · continuation
Priority: EP 0730161430 Nov 2007
Published: US 2018/0250289 A120 Dec 2018
Granted: 15 Oct 2019
Term ends: Not estimatedThe source records don’t support an estimate.

Classification12 codes

A61K 31/197
Having an amino group: the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA],…
A61K 9/0053
Galenical forms characterised by the site of application: mouth and digestive tract, i.e. intraoral and peroral administration
A61K 9/0095
Galenical forms not covered by A61K9/02 - A61K9/7023: drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets…
A61K 9/08
Medicinal preparations characterised by special physical form: solutions

Family

Application60/991,800Us provisional application · filed 3 Dec 2007
PCT/EP2008/066468Parent of this continuation · filed 28 Nov 2008
Application14/627,229Parent of this continuation · filed 20 Feb 2015
US 8,992,891 B2Parent of this continuation · filed 30 Mar 2015
Application15/966,848Parent of this continuation · filed 30 Apr 2018
US 2018/0360785 A1Pre-grant publication · published 20 Dec 2018
Application12/744,962Parent of this continuation
US 10,322,101 B2Related patent
US 2010/0310641 A1Published application
US 2015/0157626 A1Published application
US 2018/0250289 A1Published application
US 10,441,558 B2This patent

From the US filing history. Foreign family members aren’t listed.

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