Nanofibrous materials as drug, protein, or genetic release vehicles

A method of forming a fabricated textile comprising nanofibers by electrospinning perfusion, the method comprising the steps of:

• dissolving 19-20% weight per volume of a non-biodegradable polymer in hexafluoroisopropanol to provide an admixture, the dissolving occurring at an ice-cold temperature, wherein the non-biodegradable polymer is not polytetrafluoroethylene, polypropylene, or polyethylene;
• loading the admixture into an electrospinning perfusion instrument which can be set at a specified flow rate;
• applying an electric current of 15-20 kV to a needle of the electrospinning perfusion instrument;
• perfusing the admixture onto a target surface at the specified flow rate, the step of perfusing occurring at a temperature between about 20° C. and about 50° C. to provide a perfused nanofiber having a diameter from 100 nm to 3000 nm;
• and
• permitting trace hexafluoroisopropanol to be removed from the perfused nanofiber to form a fabricated textile.