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US 10,441,537 B2Granted
Unit doses, aerosols, kits, and methods for treating heart conditions by pulmonary administration
AssigneeInCarda Therapeutics, Inc.
InventorsCarlos Schuler, Rangachari Narasimhan, Luiz Belardinelli, Prashanti Madhavapeddi
Life of this patent
Estimating the term…
Abstract
Methods of treating a heart condition include administering by inhalation an effective amount of at least one antiarrhythmic pharmaceutical agent to a patient in need thereof. Nebulized drug product and kits are also contemplated.
Claims23
An inhalation pharmaceutical composition comprising a unit dose of an antiarrhythmic agent in a liquid solution that is therapeutically effective for treating atrial arrhythmia in a human subject in need thereof, wherein said antiarrhythmic agent is selected from the group consisting of:
- flecainide, a salt thereof, and a solvate thereof, wherein said unit dose of said antiarrhythmic agent is about 50 mg to about 350 mg, wherein a concentration of said antiarrhythmic agent in said unit dose is about 35 to about 60 mg/mL, and wherein said pharmaceutical composition is formulated for administration via inhalation.
Dependencies are inferred from the claim text.