US 10,441,459 B2Granted

Methods and devices for activating brown adipose tissue with cooling

AssigneesEthicon Endo-Surgery, Inc., The General Hospital Corporation

InventorsTaylor W. Aronhalt, Lee M. Kaplan, Nicholas Stylopoulos, Jason L. Harris, Dwight Henninger, James W. Voegele, Mark S. Ortiz

Life of this patent

Estimating the term…

patentgrep

Loading patent…

Abstract

Methods and devices are provided for activating brown adipose tissue (BAT) with cooling. Generally, the methods and devices can activate BAT to increase thermogenesis, e.g., increase heat production in the patient, which over time can lead to weight loss and/or improved metabolic function. In one embodiment, a medical device is provided that activates BAT by cooling tissue having a high density of cold sensitive thermoreceptors and/or by cooling BAT depots directly, thereby increasing thermogenesis in the BAT and inducing weight loss and/or improved metabolic function through energy expenditure.

Claims19

Dependent claims

A medical method, comprising:

positioning a cooling device in contact with tissue of a patient in a selected region of the patient's body that has a high density of cold sensitive thermoreceptors, wherein the cooling device includes a cold pack or a bandage assembly;
and
activating the cooling device to lower a temperature of the tissue in the selected region by a predetermined amount and for a predetermined treatment period that is sufficient to activate brown adipose tissue and increase energy expenditure of the brown adipose tissue, wherein the cooling device is activated in response to a trigger event including at least one of a change in the patient's tissue impedance and the patient falling asleep.

Dependencies are inferred from the claim text.

Facts

Application: 13/977,555Filed 21 Dec 2011 · us provisional application
Priority: 29 Dec 2010
Published: US 2015/0119849 A130 Apr 2015
Granted: 15 Oct 2019
Term ends: Not estimatedThe source records don’t support an estimate.

Classification9 codes

A61F 7/10
Heating or cooling appliances for medical or therapeutic treatment of the human body: cooling bags, e.g. ice-bags
A61F 7/106
Cooling bags, e.g. ice-bags: self-cooling, e.g. using a chemical reaction
A61F 2007/0035
Arm or parts thereof: wrist
A61F 2007/0036
Arm or parts thereof: hand

Family

Application61/428,013Us provisional application · filed 29 Dec 2010
US 2015/0119849 A1Pre-grant publication · published 30 Apr 2015
US 10,441,459 B2This patent

From the US filing history. Foreign family members aren’t listed.

Timeline

Citations

Open elsewhere

Building an agent or pulling many patents? Use the API or MCP server instead of scraping pages. Get an API key