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US 10,441,412 B2Granted
Vascular implant and delivery system
AssigneeEdwards Lifesciences CardiAQ LLC
InventorsArshad Quadri, J. Brent Ratz
Life of this patent
Estimating the term…
Abstract
A vascular implant for replacing a native heart valve comprises a self expanding stent supporting a valve body having leaflets. The stent preferably comprises an anchoring structure configured to prevent the implant from passing through the valve annulus. For delivery, the implant is compacted within a delivery device and secured at one end. During delivery the implant is partially released from the delivery device, and positioning of the implant can be verified prior to full release. The implant can be at least partially resheathed and repositioned if desired.
Claims19
A system for replacing a native valve, the system comprising:
- a replacement valve for delivery to the native valve to be secured relative to a native valve annulus, the replacement valve comprising:
- an expandable frame comprising a proximal end and a distal end and a longitudinal axis extending therethrough, the frame shaped to radially expand and collapse for deployment within the native valve annulus;
- a plurality of distal anchors connected to the expandable frame and sized to contact the native valve on a first side of the native valve annulus, wherein when the expandable frame is in an expanded configuration within the native valve annulus:
- at least a portion of each distal anchor extends proximally toward the proximal end of the expandable frame;
- and
- a proximalmost portion of each distal anchor is positioned radially outward from the expandable frame;
- and
- an anchoring feature configured to contact the native valve annulus, the anchoring feature being positioned proximal of locations at which the plurality of distal anchors are connected to the frame, wherein the anchoring feature comprises an enlarged portion of the expandable frame, the enlarged portion and the expandable frame is monolithic, the enlarged portion having a diameter greater than diameters of the proximal and distal ends of the expandable frame when the expandable frame is in an expanded configuration;
- a valve body attached to the expandable frame;
- and
- at least one locking feature extending from the expandable frame;
- wherein radial expansion of the expandable frame causes the plurality of distal anchors to draw closer to the anchoring feature;
- and
- a delivery device comprising:
- an elongate inner tube having a proximal end and a distal end;
- a locking mechanism positioned over the elongate inner tube, the locking mechanism comprising a receiving feature configured to engage the at least one locking feature of the replacement valve;
- a cover configured to surround at least the receiving feature when the at least one locking feature of the replacement valve is engaged with the receiving feature;
- and
- wherein the at least one locking feature of the replacement valve is configured to be disposed between the cover and a surface of the locking mechanism.
16 more elements
A system for replacing a native mitral valve, the system comprising:
- a replacement mitral valve for delivery to a native mitral valve to be secured relative to a native mitral valve annulus, the native mitral valve positioned between a left atrium and a left ventricle, the replacement mitral valve comprising:
- an expandable frame comprising a proximal end and a distal end and a longitudinal axis extending therethrough, the frame shaped to radially expand and collapse for deployment within the native mitral valve annulus;
- a plurality of distal anchors connected to the expandable frame and sized to contact the native mitral valve on a ventricular side of the native mitral valve annulus, wherein when the expandable frame is in an expanded configuration within the native mitral valve annulus:
- at least a portion of each distal anchor extends proximally toward the proximal end of the expandable frame;
- and
- a proximalmost portion of each distal anchor is positioned radially outward from the expandable frame;
- and
- an anchoring feature comprising an enlarged portion of the expandable frame configured to contact the native valve annulus, the enlarged portion and the expandable frame is monolithic, the enlarged portion having a diameter greater than diameters of the proximal and distal ends of the expandable frame when the expandable frame is in an expanded configuration, the enlarged portion being positioned proximal of locations at which the plurality of distal anchors are connected to the frame;
- a valve body attached to the expandable frame;
- at least one locking feature extending from the expandable frame;
- wherein radial expansion of the expandable frame causes the plurality of distal anchors to draw closer to the anchoring feature;
- and
- a delivery device comprising:
- an elongate inner tube having a proximal end and a distal end;
- a locking mechanism positioned over the elongate inner tube, the locking mechanism comprising a capture slot sized to receive and engage the at least one locking feature of the replacement mitral valve;
- and
- a cover configured to surround at least the capture slot when the at least one locking feature of the replacement mitral valve is engaged with the capture slot;
- wherein the at least one locking feature of the replacement mitral valve is configured to be disposed between the cover and a surface of the locking mechanism.
15 more elements
A system for replacing a native valve, the system comprising:
- a replacement valve for delivery to the native valve to be secured relative to a native valve annulus, the replacement valve comprising:
- an expandable frame comprising a proximal end and a distal end and a longitudinal axis extending therethrough, the frame shaped to radially expand and collapse for deployment within the native valve annulus;
- a plurality of distal anchors connected to the expandable frame and sized to contact the native valve on a first side of the native valve annulus, wherein when the expandable frame is in an expanded configuration within the native valve annulus:
- at least a portion of each distal anchor extends proximally toward the proximal end of the expandable frame;
- and
- a proximalmost portion of each distal anchor is positioned radially outward from the expandable frame, and wherein the proximalmost portion of each distal anchor is atraumatic;
- and
- an anchoring feature configured to contact the native valve annulus, the anchoring feature being positioned proximal of locations at which the plurality of distal anchors are connected to the frame, wherein the anchoring feature comprises an enlarged portion of the expandable frame, the enlarged portion and the expandable frame is monolithic, the enlarged portion having a diameter greater than diameters of the proximal and distal ends of the expandable frame when the expandable frame is in an expanded configuration;
- a valve body attached to the expandable frame;
- and
- at least one locking feature extending from the expandable frame;
- wherein radial expansion of the expandable frame causes the plurality of distal anchors to draw closer to the anchoring feature;
- and
- a delivery device comprising:
- an elongate inner tube having a proximal end and a distal end;
- a locking mechanism positioned over the elongate inner tube, the locking mechanism comprising a receiving feature configured to engage the at least one locking feature of the replacement valve;
- a cover configured to surround at least the receiving feature when the at least one locking feature of the replacement valve is engaged with the receiving feature;
- and
- wherein the at least one locking feature of the replacement valve is configured to be disposed between the cover and a surface of the locking mechanism.
16 more elements
A system for replacing a native valve, the system comprising:
- a replacement valve for delivery to the native valve to be secured relative to a native valve annulus, the replacement valve comprising:
- an expandable frame comprising a proximal end and a distal end and a longitudinal axis extending therethrough, the frame shaped to radially expand and collapse for deployment within the native valve annulus;
- a plurality of distal anchors connected to the expandable frame and sized to contact the native valve on a first side of the native valve annulus, wherein when the expandable frame is in an expanded configuration within the native valve annulus:
- at least a portion of each distal anchor extends proximally toward the proximal end of the expandable frame;
- and
- a proximalmost portion of each distal anchor is positioned radially outward from the expandable frame;
- and
- an anchoring feature configured to contact the native valve annulus, the anchoring feature being positioned proximal of locations at which the plurality of distal anchors are connected to the frame;
- a valve body attached to the expandable frame;
- and
- at least one locking feature extending from the expandable frame;
- wherein radial expansion of the expandable frame causes the plurality of distal anchors to draw closer to the anchoring feature;
- and
- a delivery device comprising:
- an elongate inner tube having a proximal end and a distal end;
- a locking mechanism positioned over the elongate inner tube, the locking mechanism comprising a receiving feature configured to engage the at least one locking feature of the replacement valve, wherein the receiving feature comprises a capture slot configured to engage the at least one locking feature of the replacement valve, and wherein the receiving feature comprises a plurality of guide slots configured to receive a portion of the replacement valve when the at least one locking feature is engaged with the capture slot, the capture slot being proximal to the one or more guide slots;
- a cover configured to surround at least the receiving feature when the at least one locking feature of the replacement valve is engaged with the receiving feature;
- and
- wherein the at least one locking feature of the replacement valve is configured to be disposed between the cover and a surface of the locking mechanism.
16 more elements
Dependencies are inferred from the claim text.