Sensor and device for lifetime imaging and detection applications

A method, comprising:

• detecting luminance lifetime characteristics of tissue using, at least in part, an integrated circuit that detects arrival times of incident photons from the tissue by selectively segregating, based on the arrival times of incident photons, charge carriers into at least one charge carrier storage region, and
• analyzing blood glucose based upon the luminance lifetime characteristics,
• wherein detecting the luminance lifetime characteristics further comprises:
• controlling the integrated circuit to aggregate, in the at least one charge carrier storage region, a number of charge carriers generated in response to incident photons received from luminescent molecules of the tissue in response to a plurality of excitations of the luminescent molecules, respectively;
• and
• reading out a voltage corresponding to the number of charge carriers aggregated in the at least one charge carrier storage region.

A point-of-care device, comprising:

• one or more optical components;
• an integrated photodetector configured to receive, through the one or more optical components, incident photons from luminescent molecules and selectively direct, into at least one charge carrier storage region, based on arrival times of the incident photons, charge carriers generated in response to receiving the incident photons;
• and
• a processor configured to detect the arrival times of the received incident photons at the integrated photodetector to perform luminance lifetime imaging,
• wherein the integrated photodetector is configured to aggregate, in the at least one charge carrier storage region, charge carriers generated in response to incident photons received from the luminescent molecules in response to a plurality of excitations of the luminescent molecules, respectively.

A point-of-care device, comprising:

• one or more optical components;
• an integrated photodetector configured to receive, through the one or more optical components, incident photons from luminescent molecules and selectively direct, into at least one charge carrier storage region, based on arrival times of the incident photons, charge carriers generated in response to receiving the incident photons, wherein the integrated photodetector is configured to aggregate, in the at least one charge carrier storage region, charge carriers generated in response to incident photons received from the luminescent molecules in response to a plurality of excitations of the luminescent molecules, respectively;
• and
• a processor configured to detect luminance lifetime characteristics of tissue by, at least in part, detecting the arrival times of incident photons from the tissue, and wherein the processor is further configured to analyze blood glucose based upon the luminance lifetime characteristics.