Algebraic phasing of polyploids
AssigneeInternational Business Machines Corporation
InventorsLaxmi P. Parida, Filippo Utro
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AssigneeInternational Business Machines Corporation
InventorsLaxmi P. Parida, Filippo Utro
Estimating the term…
Embodiments of the present invention include method, systems and computer program products for algebraic phasing of polyploids. Aspects of the invention include receiving a matrix including a set of two or more single-nucleotide poloymorphisms (SNPs) for two or more sample organisms. Each row of the matrix is set to a ploidy based on a number of ploidies present in the two or more sample organisms. Each allele in the set of two or more SNPs is represented as a binary number. A set of algebraic rules is received, wherein the set of algebraic rules include an algebraic phasing algorithm. And the set of algebraic rules are applied to the matrix to determine a haplotype of a parent of the two or more sample organisms.
A computer-implemented method for applying algebraic rules to single-nucleotide polymorphisms (SNPs), the method comprising:
A computer system for applying algebraic rules to single-nucleotide polymorphisms (SNPs), the computer system including a processor communicatively coupled to a memory, the processor configured to:
A computer program product for applying algebraic rules to single-nucleotide polymorphisms (SNPs), the computer program product comprising a computer readable storage medium having program instructions embodied therewith, the program instructions executable by a processor to cause the processor to perform:
Dependencies are inferred from the claim text.