Back to results
US 10,371,701 B2Granted
Rotors for immunoassays
AssigneeAbaxis, Inc.
InventorsRajesh K. Mehra, Kenneth P. Aron
Life of this patent
Estimating the term…
Abstract
The present invention provides an analyte detection system for detecting target analytes in a sample. In particular, the invention provides a detection system in a rotor or disc format that utilizes a centrifugal force to move the sample through the detection system. Methods of using the rotor detection system to detect analytes in samples, particularly biological samples, and kits comprising the rotor detection system are also disclosed.
Claims20
A method for detecting an analyte in a sample comprising
- (i) adding the sample to a sample port of a device comprising the sample port and a surface, wherein the surface comprises a plurality of channels arranged radially on the surface and in fluid communication with a continuous channel arranged around the peripheral edge of the surface, each of said plurality of channels containing an immobilized capture ligand positioned at the peripheral edge of the surface, wherein the capture ligands are capable of specifically binding to the analyte in the sample and wherein the sample port is in fluid communication with each of said plurality of channels and immobilized capture ligands,
- (ii) spinning the surface and the sample port about a fixed axis to generate a centrifugal force, wherein the centrifugal force causes the sample added to the sample port to flow through the plurality of channels and come into fluid contact with the capture ligands, and
- (iii) detecting the binding of the analyte in the sample to the capture ligands.
Dependencies are inferred from the claim text.