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US 10,371,608 B2Granted
Sample preservation method and sample preservation substrate
AssigneeGE Healthcare Bio-Sciences AB
InventorsMattias Algotsson, Miles W. Burrows, Jimmy Hedin Dahlstrom, Ylva Laurin, Ronnie Palmgren, Jinyu Zou
Life of this patent
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Abstract
The invention discloses a cellulose or glass fiber paper for preservation of biological samples, which comprises 4-30 wt % of a hydrophilic branched carbohydrate polymer. It also discloses a method for preservation of biological samples by applying and drying them on the paper.
Claims19
A method for preserving a biological sample, the method comprising:
- a) providing a paper having a surface weight of 40-800 g/m2, the paper comprising cellulose fibers or glass fibers, and further comprising 4-30 percentage by weight (“wt %”) of a hydrophilic branched carbohydrate polymer in the paper wherein the carbohydrate polymer is covalently bound to the cellulose fibers or glass fibers, and wherein water extractables in the paper are 0.1-25 wt %;
- b) applying the biological sample on the paper and forming a sample spot with the applied sample absorbed on the paper;
- and
- c) drying the paper with the applied sample absorbed thereon, thereby preserving the biological sample.
1 more element
A method for preserving a biological sample, the method comprising:
- a) providing a paper comprising cellulose fibers or glass fibers, and further comprising 4-30 percentage by weight (“wt %”) of a hydrophilic branched carbohydrate polymer in the paper wherein the carbohydrate polymer is covalently bound to the cellulose fibers or glass fibers, the carbohydrate polymer is a polysucrose, and water extractables in the paper are 0.1-25 wt %;
- b) applying the biological sample on the paper and forming a sample spot with the applied sample absorbed on the paper;
- and
- c) drying the paper with the applied sample absorbed thereon, thereby preserving the biological sample.
1 more element
Dependencies are inferred from the claim text.