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US 10,370,640 B2Granted
Self-aligned fibrous scaffolds for automechanoinduction of cell cultures
AssigneeTallinn University of Technology
InventorsIrina Hussainova, Michael Gasik, Roman Ivanov
Life of this patent
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Abstract
Self-aligned fibrous scaffolds are disclosed. The scaffolds are capable of automechanoinduction of cell cultures and methods to induce authomechanoinduction in cancer cells and stem cells are disclosed as well.
Claims14
A biocompatible scaffold for multi-dimensional cultivation of cells, said scaffolds capable of automechanoinduction and comprising:
- aligned fibers oriented to form a scaffold with open porosity for the cultured cells, wherein the fibers have a diameter of 5-100 nm, and an aspect ratio more than 10000:1,
- said fibers being made of non-cytotoxic, non-carcinogenic inorganic metal oxide, and
- said fibers being self-aligned into the scaffold during its manufacturing process.
Dependencies are inferred from the claim text.