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US 10,370,431 B2Granted
Optimized factor VIII gene
AssigneeBioverativ Therapeutics Inc.
InventorsSiyuan Tan, Robert T. Peters
Life of this patent
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Abstract
The present invention provides codon optimized Factor VIII sequences, vectors and host cells comprising codon optimized Factor VIII sequences, polypeptides encoded by codon optimized Factor VIII sequences, and methods of producing such polypeptides.
Claims16
An isolated nucleic acid molecule comprising a nucleotide sequence having at least 96% sequence identity to SEQ ID NO:2, wherein the nucleotide sequence encodes a polypeptide with Factor VIII activity.
Dependencies are inferred from the claim text.