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US 10,370,395 B2Granted
Cymanquine compounds and derivatives thereof and uses thereof
AssigneeUniversity of Vermont and State Agricultural College
InventorsWilliam E. Geiger, Kevin Lam, Jon E. Ramsey, Claire F. Verschraegen
Life of this patent
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Abstract
Organometallic compounds comprising a chloroquinoline moiety and uses the compounds. The compounds are, for example, manganese or rhenium complexes of a ligand comprising a chloroquinoline moiety. The compounds can be used in, for example, methods of inhibiting cell growth.
Claims10
A compound having the formula:
- where:
- M is Mn or Re,
- L is a neutral, two-electron donor ligand,
- R1 is an amine-substituted alkyl group,
- R2 is H, (CH2)nCH3, wherein n is 0 to 20, OMe, OEt, OPh, Ph, CHO, COMe, COPh, CH2OH, CO2H, CO2Me, CO2Et, CH2Ph, NH2, NMe2, NEt2, C6H4Me, C6H4OMe, NH2COMe, F, Cl, Br, or I;
- and
- E is a linker moiety connecting the cyclopentadienyl moiety with the chloroquinoline moiety.
4 more elements
Dependencies are inferred from the claim text.